BioinformaticsNature AgingPeer-reviewed
A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking
Albert Higgins‐Chen, Kyra Thrush, Yunzhang Wang…·Morgan E. Levine
This paper introduces a computational method to improve the reliability of epigenetic clocks by using principal component analysis, showing reduced technical noise and better performance in longitudinal studies.
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