Author

Makoto Shimozawa

Karolinska InstitutetORCID 0000-0001-9618-0533Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Per NilssoniD· 2 shared Aline Petrich· 1 shared Bengt G. WinbladiD· 1 shared Catarina Moreira Pinho· 1 shared Erik Berger· 1 shared Erika BereczkiiD· 1 shared Giacomo DentoniiD· 1 shared Hiroki SasaguriiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Per NilssonORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 7, 2023

Early mitochondrial dysfunction proceeds neuroinflammation, synaptic alteration, and autophagy impairment in hippocampus of App knock-in Alzheimer mouse models

Luana Naia, Makoto Shimozawa, Erika Bereczki…·Per Nilsson

This study identifies early mitochondrial dysfunction, neuroinflammation, and autophagy impairment in App knock-in Alzheimer's mouse models through time-course transcriptome analysis.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 9, 2020

Somatostatin receptor subtypes 1 and 4 redundantly regulate neprilysin, the major amyloid beta-degrading enzyme, in brain

Per Nilsson, Karin Margareta Sörgjerd, Naomasa Kakiya…·Takaomi C. Saido

This study identifies SST1 and SST4 as redundant regulators of neprilysin, a key amyloid beta-degrading enzyme, and shows that targeting these receptors reduces Aβ pathology and improves cognition in an AD mouse model.

11 citations

mouseexperimental assay

𝕏 PostBluesky