Senthil Arumugam

The paper introduces MOSAIC, a multimodal adaptive optical microscope that enables non-invasive imaging across biological scales in live specimens.

The paper identifies mechanisms of mitochondrial streaming in oocytes, showing actin-driven and chromatin-associated pathways that pattern mitochondrial distribution.

This study investigates the functional differences between MTX1 and MTX3, showing that their loss leads to distinct mitochondrial phenotypes and that both depend on MTX2 for stability.

This paper introduces Airy beam light sheet microscopy to image subcellular dynamics in large tissues with high spatial and temporal resolution across multiple organisms and biological processes.

This study shows SNX9 selectively binds PI(3,4)P2 lipids through a non-canonical interface, protecting them from hydrolysis during membrane remodeling.

The paper introduces SAM-DNMT3A, a CRISPR-based method to induce global DNA methylation, and shows it exploits a vulnerability in ER-positive breast cancers.

This study uses QSLIP to map amyloid-beta oligomer membrane insertion, finding toxicity correlates with amino-terminal penetration depth.

The paper identifies FUG1, AL3, and LHP1 as essential components for repeat-expansion induced epigenetic silencing in Arabidopsis thaliana.