Author

Javier Franco‐Pérez

Centre Hospitalier Universitaire VaudoisORCID 0000-0001-9670-8502Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 3 Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:mixed model· 1

Frequent Co-Authors

Jeannette JanseniD· 3 shared Marie‐Catherine VozeniniD· 3 shared Paola Ballesteros‐ZebadúaiD· 3 shared Veljko GriljiD· 3 shared Benoît PetitiD· 2 shared Charles L. LimoliiD· 2 shared Aaron B. SimoniD· 1 shared Adam KimbleriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersCancer Biology

Jeannette JansenORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 1, 2026

✦ In-depth digest

Differential and regionally distinct molecular responses distinguish FLASH and conventional RT in a medulloblastoma model while preserving therapeutic outcomes

Michèle Knol, Javier Franco‐Pérez, Aymeric Almeida…·Paola Ballesteros‐Zebadúa

Hypo-fractionated FLASH and conventional radiotherapy (3x10 Gy) each ablated orthotopic human medulloblastoma in nude mice; FLASH evoked distinct microglial and hippocampal transcriptional programs and less neuroinflammation.

DOI 10.64898/2026.03.16.712103

mousehuman

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BiochemistrybioRxivPreprintMar 16, 2026

FLASH Radiotherapy is faster than a heartbeat: A compartmental model to illustrate the interplay between tissue oxygen perfusion and ultra-high dose rate effects.

Paola Ballesteros‐Zebadúa, Jeannette Jansen, Veljko Grilj…·Ramin Abolfath

The paper develops a compartmental model to simulate oxygen perfusion and its interaction with ultra-high dose rate radiation in FLASH Radiotherapy, showing a sigmoidal dose-rate-response curve for lipid peroxidation.

1 citation

mouseimaging

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NeurosciencebioRxivPreprintFeb 1, 2025

Differentiating unirradiated mice from those exposed to conventional or FLASH radiotherapy using MRI

Jeannette Jansen, Adam Kimbler, Olivia G.G. Drayson…·Paola Ballesteros‐Zebadúa

This study uses MRI to differentiate between unirradiated mice and those exposed to conventional or FLASH radiotherapy, finding distinct brain changes after conventional but not FLASH treatment.

DOI 10.1101/2025.02.01.636061

mouseimaging

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