Author

Charles L. Limoli

University of California, IrvineORCID 0000-0002-1321-4142Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Marie‐Catherine VozeniniD· 5 shared Benoît PetitiD· 3 shared Jonathan Ollivier· 3 shared Louis V. KunziD· 3 shared Aymeric AlmeidaiD· 2 shared Billy W. LooiD· 2 shared Javier Franco‐PéreziD· 2 shared Jeannette JanseniD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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5 shared papersCancer Biology

Marie‐Catherine VozeninORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 1, 2026

✦ In-depth digest

Differential and regionally distinct molecular responses distinguish FLASH and conventional RT in a medulloblastoma model while preserving therapeutic outcomes

Michèle Knol, Javier Franco‐Pérez, Aymeric Almeida…·Paola Ballesteros‐Zebadúa

Hypo-fractionated FLASH and conventional radiotherapy (3x10 Gy) each ablated orthotopic human medulloblastoma in nude mice; FLASH evoked distinct microglial and hippocampal transcriptional programs and less neuroinflammation.

DOI 10.64898/2026.03.16.712103

mousehuman

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMay 19, 2026

Neuroprotection following FLASH-RT may be mediated by sustained glutamate receptor AMPAR activation in CA3 neurons

Louis V. Kunz, Aymeric Almeida, Michèle Knol…·Marie‐Catherine Vozenin

This study investigates FLASH-RT's neuroprotective effects by showing sustained AMPAR activation in CA3 neurons through early transcriptional upregulation of glutamate receptor genes.

DOI 10.64898/2026.05.15.725423

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyRadiotherapy and OncologyPeer-reviewedMay 20, 2025

Modification of the microstructure of the CERN- CLEAR-VHEE beam at the picosecond scale modifies ZFE morphogenesis but has no impact on hydrogen peroxide production.

Houda Kacem, L. L. Kunz, Pierre Korysko…·Marie‐Catherine Vozenin

This study investigates how modifying the microstructure of a CERN CLEAR-VHEE beam at the picosecond scale affects zebrafish embryo morphogenesis and hydrogen peroxide production.

20 citationstop 1%

zebrafishexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 1, 2025

Differentiating unirradiated mice from those exposed to conventional or FLASH radiotherapy using MRI

Jeannette Jansen, Adam Kimbler, Olivia G.G. Drayson…·Paola Ballesteros‐Zebadúa

This study uses MRI to differentiate between unirradiated mice and those exposed to conventional or FLASH radiotherapy, finding distinct brain changes after conventional but not FLASH treatment.

DOI 10.1101/2025.02.01.636061

mouseimaging

𝕏 PostBluesky

Molecular BiologyRadiotherapy and OncologyPeer-reviewedNov 1, 2023

FLASH-RT does not affect chromosome translocations and junction structures beyond that of CONV-RT dose-rates

Paul G. Barghouth, Stavros Melemenidis, Pierre Montay‐Gruel…·Richard L. Frock

This study shows FLASH-RT and CONV-RT produce similar levels and proportions of chromosome translocations and junction structures under various oxygen conditions.

22 citations

humanDNA methylation

𝕏 PostBluesky