Author

Veljko Grilj

Centre Hospitalier Universitaire VaudoisORCID 0000-0001-6573-8063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:imaging· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Approach:mixed model· 1

Frequent Co-Authors

Javier Franco‐PéreziD· 3 shared Jeannette JanseniD· 3 shared Marie‐Catherine VozeniniD· 3 shared Paola Ballesteros‐ZebadúaiD· 3 shared Benoît PetitiD· 2 shared Charles L. LimoliiD· 2 shared Aaron B. SimoniD· 1 shared Adam KimbleriD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

Javier Franco‐PérezORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 1, 2026

✦ In-depth digest

Differential and regionally distinct molecular responses distinguish FLASH and conventional RT in a medulloblastoma model while preserving therapeutic outcomes

Michèle Knol, Javier Franco‐Pérez, Aymeric Almeida…·Paola Ballesteros‐Zebadúa

Hypo-fractionated FLASH and conventional radiotherapy (3x10 Gy) each ablated orthotopic human medulloblastoma in nude mice; FLASH evoked distinct microglial and hippocampal transcriptional programs and less neuroinflammation.

DOI 10.64898/2026.03.16.712103

mousehuman

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BiochemistrybioRxivPreprintMar 16, 2026

FLASH Radiotherapy is faster than a heartbeat: A compartmental model to illustrate the interplay between tissue oxygen perfusion and ultra-high dose rate effects.

Paola Ballesteros‐Zebadúa, Jeannette Jansen, Veljko Grilj…·Ramin Abolfath

The paper develops a compartmental model to simulate oxygen perfusion and its interaction with ultra-high dose rate radiation in FLASH Radiotherapy, showing a sigmoidal dose-rate-response curve for lipid peroxidation.

1 citation

mouseimaging

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Cancer BiologyRadiotherapy and OncologyPeer-reviewedNov 3, 2025

Decrease in dose per fraction impairs the FLASH sparing effect in murine intestine model

Anouk Sesink, R. Geyer, P Devanand…·Veljko Grilj

This study shows that FLASH radiotherapy's protective effect on mouse intestines decreases with more fractions and lower doses per fraction, with no sparing observed in a ten-fraction regimen.

14 citationstop 1%

mouseexperimental assay

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NeurosciencebioRxivPreprintFeb 1, 2025

Differentiating unirradiated mice from those exposed to conventional or FLASH radiotherapy using MRI

Jeannette Jansen, Adam Kimbler, Olivia G.G. Drayson…·Paola Ballesteros‐Zebadúa

This study uses MRI to differentiate between unirradiated mice and those exposed to conventional or FLASH radiotherapy, finding distinct brain changes after conventional but not FLASH treatment.

DOI 10.1101/2025.02.01.636061

mouseimaging

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GeneticsScientific ReportsPeer-reviewedJun 16, 2023

Proton and alpha radiation-induced mutational profiles in human cells

Tiffany Myriam Delhomme, Maia Munteanu, Manuela Buonanno…·Fran Supek

This study examines mutational profiles in human cells exposed to proton and alpha radiation, finding subtle changes in mutation spectra and distributions but not overall increased mutation rates.

12 citations

humanwhole-genome sequencing

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