Raphaëlle Laureau

Two retrotransposon-derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity

This study shows that PNMA1 and PNMA4, derived from retrotransposons, are essential for reproductive capacity, as their absence leads to subfertility and hormonal changes in mice and associations with reproductive traits in humans.

Rie1 and Sgn1 form an RNA-binding complex that enforces the meiotic entry cell fate decision

This study identifies Rie1 and Sgn1 as RNA-binding proteins that enforce meiotic entry by post-transcriptionally enhancing Ime1 protein levels in budding yeast.

Aborting meiosis overcomes hybrid sterility

Aborting meiosis followed by return-to-growth promotes genome-wide recombination in sterile yeast hybrids, enabling adaptation and genetic mapping.