Author

Szu‐Hsueh Lai

Utrecht UniversityORCID 0000-0001-9698-1496Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Albert J. R. HeckiD· 2 shared Albert BondtiD· 1 shared Aleksandar AntanasijeviciD· 1 shared Alena KhmelinskaiaiD· 1 shared Andrew B. WardiD· 1 shared Andrew J. BorstiD· 1 shared Andrew M. WatkinsiD· 1 shared Arjan Barendregt· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

Albert J. R. HeckORCID

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2 papers

Recent·Most cited

BioengineeringNature Structural & Molecular BiologyPeer-reviewedFeb 26, 2025

Local structural flexibility drives oligomorphism in computationally designed protein assemblies

Alena Khmelinskaia, Neville P. Bethel, Farzad Fatehi…·Neil P. King

This study shows that structural flexibility in computationally designed protein assemblies leads to multiple architectures, expanding their functional possibilities.

23 citationstop 3%

cryo-EMmechanistic / dynamical model

𝕏 PostBluesky

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedDec 6, 2023

CD5L is a canonical component of circulatory IgM

Nienke Oskam, Maurits A. den Boer, Marie Vestergaard Lukassen…·Albert J. R. Heck

The paper identifies CD5L as a component of circulatory IgM, showing it forms a complex with J-chain-containing pentamers and affects IgM receptor binding.

47 citationstop 1%

humanproteomics

𝕏 PostBluesky