Author
Amsterdam UMC Location University of AmsterdamORCID 0000-0001-5937-2608Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Nienke Oskam, Jim B. D. Keijser, Marij Streutker…·Theo Rispens
This paper develops sensitive ELISAs to quantify J-chain-containing IgA and IgM, revealing that 10% of circulating IgA is polymeric and enabling high-throughput analysis of polymeric IgA responses.
Camiel Göbel, Rachele Niccolai, Marnix H. P. de Groot…·Heinz Jacobs
This study shows that targeting DOT1L and EZH2 together disrupts the germinal center identity of GCB-DLBCL cells, leading to a cell-identity crisis and reduced tumor growth in vivo.
Nienke Oskam, Maurits A. den Boer, Marie Vestergaard Lukassen…·Albert J. R. Heck
The paper identifies CD5L as a component of circulatory IgM, showing it forms a complex with J-chain-containing pentamers and affects IgM receptor binding.