Author

Isabelle Rouiller

Australian Research CouncilORCID 0000-0002-1288-8575Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:cryo-EM· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Amit Kumar DasiD· 1 shared Ayushi Saini· 1 shared Ching‐Seng AngiD· 1 shared Elizabeth HindeiD· 1 shared Joydeep BaraliD· 1 shared Kalyan ShobhanaiD· 1 shared Paul J. McMillaniD· 1 shared Rémi VuillemotiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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1 shared paperBiochemistry

Amit Kumar DasORCID

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2 papers

Recent·Most cited

BiochemistryNucleic Acids ResearchPeer-reviewedNov 30, 2025

Bringing the Ends together: Cryo-EM structures of mycobacterial Ku in complex with DNA define its role in NHEJ synapsis

Joydeep Baral, Ching‐Seng Ang, Paul J. McMillan…·Isabelle Rouiller

This study presents cryo-EM structures of mycobacterial Ku (mKu) in complex with DNA, revealing its role in NHEJ synapsis and identifying key residues for DNA binding and synaptic assembly.

2 citations

cryo-EMmicroscopy & imaging analysis

𝕏 PostBluesky

BioinformaticsbioRxivPreprintFeb 25, 2023

MDTOMO: Continuous conformational variability analysis in cryo electron subtomogram data using flexible fitting based on Molecular Dynamics simulations

Rémi Vuillemot, Isabelle Rouiller, Slavica Jonić

MDTOMO analyzes continuous conformational variability in cryo-ET subtomograms using MD simulations to generate atomic-scale models and free-energy landscapes.

2 citations

electronic health recordsstatistical model

𝕏 PostBluesky