Author

Jiancan Yu

Sun Yat-sen UniversityORCID 0000-0001-9723-6113Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:mechanistic / dynamical model· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Chenjie XuiD· 2 shared Kai WuiD· 2 shared Qizheng ZhangiD· 2 shared Tianrui Zhao· 2 shared Wenjing Hou· 2 shared Xunwu HuiD· 2 shared Ye ZhangiD· 2 shared Junchao Zhi· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersBiophysics

Chenjie XuORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 8, 2026

Integrin-engaged Cellular Patches Mechanically Impose a Mitochondrial Respiratory Bottleneck to Suppress Cancer Cell Motility

Qizheng Zhang, Sona Rani Roy, Tianrui Zhao…·Ye Zhang

This study shows that integrin-mediated mechanotransduction through supramolecular ligand clustering limits mitochondrial respiratory capacity, thereby suppressing cancer cell motility and tumor growth.

DOI 10.64898/2026.07.03.736349

humanproteomics

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BioengineeringbioRxivPreprintNov 21, 2025

Engineering Apical Integrin-binding Cellular Patches to Directed Cell Reprogramming via Mechanical Remodeling

Junchao Zhi, Tianrui Zhao, Wenjing Hou…·Ye Zhang

This paper develops ECM-mimetic cellular patches that reprogram mesenchymal stem cells into neurons through mechanical remodeling without genetic or chemical induction.

DOI 10.1101/2025.11.21.689608

humanspatial transcriptomics

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