BiophysicsbioRxivPreprint
Integrin-engaged Cellular Patches Mechanically Impose a Mitochondrial Respiratory Bottleneck to Suppress Cancer Cell Motility
Qizheng Zhang, Sona Rani Roy, Tianrui Zhao…·Ye Zhang
This study shows that integrin-mediated mechanotransduction through supramolecular ligand clustering limits mitochondrial respiratory capacity, thereby suppressing cancer cell motility and tumor growth.
DOI 10.64898/2026.07.03.736349