Author

Xunwu Hu

Chinese Academy of SciencesORCID 0000-0002-8822-9015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Approach:mechanistic / dynamical model· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Qizheng ZhangiD· 3 shared Wenjing Hou· 3 shared Ye ZhangiD· 3 shared Chenjie XuiD· 2 shared Jiancan YuiD· 2 shared Kai WuiD· 2 shared Tianrui Zhao· 2 shared Jie Gao· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBioengineering

Qizheng ZhangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Terminal Modification Reprograms Supramolecular Organization of Integrin Ligand Assemblies to Shape Cell Migration

Ziyi Su, Yanling Lin, Zhu Zhu, Xunwu Hu, Wenjing Hou, Qizheng Zhang, Yanbin Cai, Jie Gao, Zhimou Yang, Ye Zhang

This study shows that terminal modifications of integrin ligands can reprogram their supramolecular organization and function, affecting cell migration without altering the sequence.

bioRxiv · Sep 29, 2026 · PreprintBioengineering

Integrin-engaged Cellular Patches Mechanically Impose a Mitochondrial Respiratory Bottleneck to Suppress Cancer Cell Motility

Qizheng Zhang, Sona Rani Roy, Tianrui Zhao, Wenjing Hou, Chenjie Xu, Jiancan Yu, Kai Wu, Xunwu Hu, Ye Zhang

This study shows that integrin-mediated mechanotransduction through supramolecular ligand clustering limits mitochondrial respiratory capacity, thereby suppressing cancer cell motility and tumor growth.

bioRxiv · Jul 8, 2026 · PreprintBiophysics

Engineering Apical Integrin-binding Cellular Patches to Directed Cell Reprogramming via Mechanical Remodeling

Junchao Zhi, Tianrui Zhao, Wenjing Hou, Qizheng Zhang, Zhen Gao, Jiancan Yu, Kai Wu, Chenjie Xu, Xunwu Hu, Ye Zhang

This paper develops ECM-mimetic cellular patches that reprogram mesenchymal stem cells into neurons through mechanical remodeling without genetic or chemical induction.

bioRxiv · Nov 21, 2025 · PreprintBioengineering