Author

Darcy B. Pooler

Dartmouth–Hitchcock Medical CenterORCID 0000-0001-9762-9013Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Adrianna L. De La TorreiD· 1 shared Catherine C.Y. ChangiD· 1 shared Dylan B. NessiD· 1 shared Kimberley S. SamkoeiD· 1 shared Lionel D. LewisiD· 1 shared Sanjana PannemiD· 1 shared Ta‐Yuan ChangiD· 1 shared Thao Nguyen Thanh HuynhiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Adrianna L. De La TorreORCID

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1 paper

Recent·Most cited

Stealth liposomes encapsulating a potent ACAT1/SOAT1 inhibitor F12511: pharmacokinetic, biodistribution and toxicity studies in wild-type mice, and efficacy studies in triple transgenic Alzheimer Disease mice.

Adrianna L. De La Torre, Thao Nguyen Thanh Huynh, Catherine C.Y. Chang, Darcy B. Pooler, Dylan B. Ness, Lionel D. Lewis, Sanjana Pannem, Yichen Feng, Kimberley S. Samkoe, William F. Hickey, Ta‐Yuan Chang

This study evaluates a nanoparticle-formulated ACAT1 inhibitor in mice, showing brain delivery and reduced AD pathology without toxicity.

bioRxiv · May 2, 2023 · PreprintNeuroscience