Author

Kimberley S. Samkoe

Dartmouth CollegeORCID 0000-0002-8234-2308Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Adrianna L. De La TorreiD· 1 shared Alberto J. RuiziD· 1 shared Alyssa M. RobertsiD· 1 shared Arminja Nadine KettenbachiD· 1 shared Catherine C.Y. ChangiD· 1 shared Christo Philip C. DragneviD· 1 shared Darcy B. PooleriD· 1 shared Dylan B. NessiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperNeuroscience

Adrianna L. De La TorreORCID

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3 papers

Recent·Most cited

BiochemistryJournal of Biomedical OpticsPeer-reviewedJul 29, 2026

Indocyanine green excitation-emission matrix characterization: excitation-dependent emission shifts and application-specific spectra

Alberto J. Ruiz, Sophie A. Lyon, Ethan P. M. LaRochelle, Kimberley S. Samkoe

This paper characterizes indocyanine green (ICG) excitation-emission matrices in different microenvironments, showing excitation-dependent emission and its implications for fluorescence-guided surgery.

DOI 10.1117/1.jbo.31.7.077003

imagingexperimental assay

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Cancer BiologyCancer ResearchPeer-reviewedJan 8, 2025

Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation

Steven S. Tau, Mary Dickinson Chamberlin, Huijuan Yang…·Todd W. Miller

This study identifies mitochondrial oxidative phosphorylation as a metabolic vulnerability in endocrine-tolerant persister ER+ breast cancer cells, suggesting therapeutic targeting of mitochondrial function could prevent recurrence.

29 citationstop 1%

humanproteomics

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NeurosciencebioRxivPreprintMay 2, 2023

Stealth liposomes encapsulating a potent ACAT1/SOAT1 inhibitor F12511: pharmacokinetic, biodistribution and toxicity studies in wild-type mice, and efficacy studies in triple transgenic Alzheimer Disease mice.

Adrianna L. De La Torre, Thao Nguyen Thanh Huynh, Catherine C.Y. Chang…·Ta‐Yuan Chang

This study evaluates a nanoparticle-formulated ACAT1 inhibitor in mice, showing brain delivery and reduced AD pathology without toxicity.

2 citations

mouseexperimental assay

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