Author
Harvard UniversityORCID 0000-0001-9904-0966Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Miguel A. Gonzalez‐Lozano, Kelsey L. Hickey, Ernst W. Schmid…·J. Wade Harper
The paper develops GolgiFold, a structure-based PPI map of human Golgi proteins, identifying over 1,800 interactions and confirming new protein contacts through experimental validation.
Zebulon G. Levine, Stuti Khandwala, Christina J. Zhang…·Jonathan S. Weissman
The paper identifies a cell-state-dependent pathway for degrading ER-retained 60S ribosomal subunits through UFMylation loss and the action of TLSD1.
Kelsey L. Hickey, Alexandra Panov, Enya Miguel Whelan…·J. Wade Harper
This study identifies UBE3C and NRF1-dependent proteasomal pathways that regulate acute protein aggregate turnover in response to misfolded protein accumulation.
Kelsey L. Hickey, Kimberley Dickson, J. Zachery Cogan…·Kamena K. Kostova
The paper identifies GIGYF2 and 4EHP as translation inhibitors that suppress re-initiation of defective mRNAs, aiding ribosome-associated quality control and preventing toxic protein accumulation.