Miguel A. Gonzalez‐Lozano

The paper develops GolgiFold, a structure-based PPI map of human Golgi proteins, identifying over 1,800 interactions and confirming new protein contacts through experimental validation.

The paper creates a structural interactome of human endosomes using cross-linking, mass spectrometry, and AlphaFold, identifying structural models for endosomal protein complexes.

This paper develops Endo-IP and Lyso-IP methods to profile endolysosomal proteins in induced neurons, revealing cargo and machinery involved in neurodegenerative disease.

This study shows that tomosyn regulates DCV cargo levels but not exocytosis in neurons, suggesting a role in cargo production rather than release.

The paper identifies a protein-protein interaction network in human excitatory neurons for 13 ASD risk genes, revealing novel interactions and convergent mechanisms contributing to autism spectrum disorders.

The paper identifies excessive ribosomal protein translation as a key factor in Fragile X Syndrome by showing its role in disrupting synaptic protein translation and LTD.

This study identifies SNX4 as a novel synaptic protein through localization and functional analysis in neurons.