Author

Helena Païdassi

Lyon 1 UniversitéORCID 0000-0001-9915-4365Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Dean SheppardiD· 2 shared Aditya KatewaiD· 1 shared Agnieszka CiesielskaiD· 1 shared Alessandra CastiglioniiD· 1 shared Amara LarpthaveesarpiD· 1 shared Amha AtakilitiD· 1 shared Anna Victoria MolofskyiD· 1 shared Anthony A. ChangiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Dean SheppardORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 9, 2026

Inhibition of integrin αvβ8-mediated TGFβ activation and active-TGFβ blockade promote anti-tumor immunity through distinct biological mechanisms

Kate Williams, Stephanie Mittman, Natalie S. Firmino…·Alessandra Castiglioni

The paper shows that blocking integrin αvβ8 suppresses TGFβ in tumor-draining lymph nodes and enhances DC-T cell activation, offering a new immunotherapy strategy distinct from TGFβ ligand blockade.

DOI 10.64898/2026.07.06.735099

mouseproteomics

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ImmunologybioRxivPreprintFeb 28, 2026

Type 1 and type 2 dendritic cell subsets cooperate to maintain intestinal immune tolerance via integrin αvβ8-mediated TGF-β activation

Sébastien This, Delphine Brichart-Vernos, Venla A. Väänänen…·Helena Païdassi

This study identifies cDC1 and cDC2 as essential for TGF-β activation and pTreg induction in the gut, maintaining immune tolerance.

1 citation

mouseexperimental assay

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ImmunologyNaturePeer-reviewedSep 3, 2025

Dynamic fibroblast-immune interactions shape wound healing after brain injury

Nathan A. Ewing-Crystal, Nicholas M. Mroz, Amara Larpthaveesarp…·Ari B. Molofsky

This study identifies dynamic fibroblast-immune interactions that regulate CNS wound healing and neuroinflammation after brain injury.

65 citationstop 1%

mousespatial transcriptomics

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