Ralf Hoffmann

This study examines how metal ion environments affect the antimicrobial activity of PrAMPs against Pseudomonas aeruginosa and Escherichia coli, revealing ion-dependent changes in their mode of action.

This study identifies Drosocin as a type II PrAMP that inhibits protein synthesis termination by stalling ribosomes at stop codons, distinct from apidaecin.

The paper demonstrates that the quorum sensing peptide EntF* from gut microbiota promotes colorectal cancer metastasis in mice, identifying it as a novel mediator of microbiome-host interaction.