Author

Dharmarajan Sriram

Birla Institute of Technology and Science - Hyderabad CampusORCID 0000-0001-9970-2050Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

Anannya DhanwaliD· 1 shared Arpita Verma· 1 shared Biplab SinghaiD· 1 shared D. V. Sai Prasad· 1 shared Deborah M. Hunt· 1 shared Divya Tej SowpatiiD· 1 shared Linus AugustiniD· 1 shared Luiz Pedro S. de CarvalhoiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Anannya DhanwalORCID

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2 papers

Recent·Most cited

MicrobiologyScientific ReportsPeer-reviewedMay 28, 2024

Elucidation of the essentiality of lumazine synthase (RibH) for Mycobacterium tuberculosis survival and discovery of potent inhibitors for enhanced antimycobacterial therapy

Monica Singh, Anannya Dhanwal, Arpita Verma…·Ruchi Jain Dey

This study validates the essentiality of RibH in M. tb survival and identifies three potent RibH inhibitors that show antimycobacterial activity and synergy with first-line TB drugs.

14 citations

humanmouse

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MicrobiologyeLifePeer-reviewedDec 4, 2023

Divergent downstream biosynthetic pathways are supported by L-cysteine synthases of Mycobacterium tuberculosis

Mehak Zahoor Khan, Deborah M. Hunt, Biplab Singha…·Vinay Kumar Nandicoori

The paper identifies two non-canonical L-cysteine synthases in Mtb, CysM and CysK2, which support divergent biosynthetic pathways critical for redox stress response and survival during infection.

12 citations

humanbulk RNA-seq

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