Bruno Martorelli Di Genova

The paper surveys TOR and AMPK across 210 eukaryotes, revealing lineage-specific variations in component repertoires, sequence features, and component associations.

This paper identifies UCB-9721 as a potent inhibitor of T. gondii MyoA, showing greater potency than KNX-002 and inhibiting related apicomplexan parasites.

The paper uses single-cell RNA profiling to show in vivo-derived Toxoplasma bradyzoites undergo two cell cycles, with AP2XI-6 playing a key role in one cycle essential for cyst maturation.

This study investigates the role of equilibrative nucleoside transporters in Toxoplasma gondii, showing that TgENT1 is critical for bradyzoite differentiation and identifying it as a therapeutic target.

The paper identifies a mutation in the SARS-CoV-2 nucleocapsid protein that enhances viral infection by promoting dimer formation and altering virion structure.