Author

Nathaniel R. West

GenentechORCID 0000-0001-9991-0503Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron Wong· 1 shared Alessandra CastiglioniiD· 1 shared Alexander ArlanticoiD· 1 shared Alexander R. AbbasiD· 1 shared Andréy S. ShawiD· 1 shared Caroline WhittyiD· 1 shared Cary D. AustiniD· 1 shared Cecilia ChiuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Aaron Wong

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 9, 2026

Inhibition of integrin αvβ8-mediated TGFβ activation and active-TGFβ blockade promote anti-tumor immunity through distinct biological mechanisms

Kate Williams, Stephanie Mittman, Natalie S. Firmino…·Alessandra Castiglioni

The paper shows that blocking integrin αvβ8 suppresses TGFβ in tumor-draining lymph nodes and enhances DC-T cell activation, offering a new immunotherapy strategy distinct from TGFβ ligand blockade.

DOI 10.64898/2026.07.06.735099

mouseproteomics

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 13, 2026

Combined antagonism of Oncostatin M (OSM) and Interleukin 6 (IL-6) provides both anti-fibrotic and anti-inflammatory benefit in pulmonary fibrosis

Rojo A. Ratsimandresy, Emma Doran, Hart S. Dengler…·Mark S. Wilson

This study shows that blocking OSM and IL-6 reduces fibrosis and inflammation in pulmonary fibrosis by targeting their shared receptor and distinct pathways.

DOI 10.64898/2025.12.25.695625

mousehuman

𝕏 PostBluesky