Author

Seung‐Joo Lee

Harvard UniversityORCID 0000-0002-0027-2554Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Alfredo J. HernandeziD· 1 shared Gijs J. L. WuiteiD· 1 shared Hitoshi Mitsunobu· 1 shared Longfu XuiD· 1 shared Meindert Hugo LamersiD· 1 shared Mia UremiD· 1 shared Peter Guy WolynesiD· 1 shared Sebastian UrbanoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Alfredo J. HernandezORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Molecular BiologyPeer-reviewedSep 4, 2026

Replication of DNA containing trinucleotide repeats by the bacteriophage T7 replisome

Seung‐Joo Lee, Sebastian Urbano, Hitoshi Mitsunobu, Alfredo J. Hernandez

This study examines how the T7 bacteriophage replisome replicates DNA with CAG and CTG trinucleotide repeats, revealing differences in replication efficiency and product length.

DOI 10.1016/j.jmb.2026.170012

E. coliDNA methylation

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BiophysicsNature CommunicationsPeer-reviewedAug 12, 2025

DNA polymerase actively and sequentially displaces single-stranded DNA-binding proteins

Longfu Xu, Shikai Jin, Mia Urem…·Gijs J. L. Wuite

This study investigates how DNA polymerase displaces SSBs during replication, showing sequential displacement and the role of SSB saturation in replication efficiency.

3 citations

E. colifluorescence / live-cell microscopy

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