Author

Gwendoline Hoslett

John Radcliffe HospitalORCID 0000-0002-0030-7761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Christopher J. LordiD· 2 shared Dragomir B. KrasteviD· 2 shared Kristijan RamadaniD· 2 shared Alvin Wei Tian NgiD· 1 shared Andrea PierangeliniiD· 1 shared Andrew J. WicksiD· 1 shared Andrew N.J. TuttiD· 1 shared Cynthia X. Hou· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Christopher J. LordORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cell BiologyNature Cell BiologyPeer-reviewedJun 1, 2026

Nucleophagy removes cytotoxic trapped PARP1

Gwendoline Hoslett, Sara Tribble, Pauline Lascaux…·Kristijan Ramadan

This study identifies nucleophagy as the mechanism by which trapped PARP1 is cleared, showing that inhibiting this process re-sensitizes PARPi-resistant cells to PARPi.

6 citationstop 1%

humanproteomics

𝕏 PostBluesky

Molecular BiologyNature Cell BiologyPeer-reviewedJan 1, 2022

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

Dragomir B. Krastev, Shudong Li, Yilun Sun…·Christopher J. Lord

The paper identifies p97 ATPase as a key player in removing trapped PARP1 from chromatin, enhancing PARPi-induced cytotoxicity in homologous recombination-defective cells.

164 citationstop 1%

humanproteomics

𝕏 PostBluesky