Adam D. Cawte

Nuclear-BRITE reduces background noise in MS2-based live-cell imaging of nuclear RNAs without affecting their abundance or function.

The paper identifies a contact-mediated transfer mechanism for Xist RNA localization and spread across the X chromosome.

This study uses cryo-electron tomography to reveal the multiscale compaction and organisation of the inactive X chromosome, showing the role of histone H1 and acetylation in chromatin structure.

This study investigates SMCHD1's chromatin interactions and shows LRIF1 and ATPase activity are critical for its selective binding and epigenetic silencing functions.