Author

Jean Lucas Kremer

Boston Children's HospitalORCID 0000-0002-0053-8500Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1

Frequent Co-Authors

Alcides Euzebio Tavares XavieriD· 1 shared Alessandro PreteiD· 1 shared Andris JankevicsiD· 1 shared Angela E. TayloriD· 1 shared Antoine TabariniD· 1 shared Ashutosh Joshi· 1 shared Ayush Nigam· 1 shared Betül Haykir· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alcides Euzebio Tavares XavierORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 27, 2025

Deciphering the intra-tissue specific Collagen PTMs site-specific heterogeneity in Human Adrenal extracellular-matrix

Ashutosh Joshi, Ayush Nigam, Jean Lucas Kremer…·Trayambak Basak

This study identifies and quantifies site-specific collagen post-translational modifications (PTMs) in human adrenal extracellular matrix, revealing intra-tissue heterogeneity in PTM occupancy and potential functional implications.

DOI 10.1101/2025.10.27.684899

humanproteomics

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Cancer BiologybioRxivPreprintSep 28, 2025

Glutamine antagonism suppresses tumor growth in adrenocortical carcinoma through inhibition of de novo nucleotide biosynthesis

Vasileios Chortis, Kleiton Silva Borges, Cong-Hui Yao…·David T. Breault

This study identifies glutamine antagonism as a therapeutic strategy for adrenocortical carcinoma by inhibiting de novo nucleotide biosynthesis and inducing DNA damage.

1 citation

humanmouse

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