Kleiton Silva Borges

This study identifies EGFR inhibitors as inducers of enteroendocrine cell differentiation, linking their use to treatment-associated diarrhea through STAT1 signaling activation.

This study shows that β-Catenin-driven hyperplasia in the adrenal cortex is mediated through Rho-ROCK signaling and Cat-dependent stabilization of adherens junctions.

This study identifies glutamine antagonism as a therapeutic strategy for adrenocortical carcinoma by inhibiting de novo nucleotide biosynthesis and inducing DNA damage.

This paper identifies DLK1 as a marker of adrenocortical stem/progenitor cells that predicts malignancy in adrenocortical carcinoma and is detectable in patient serum.

This study identifies WNT2B as a key regulator of adrenal aldosterone production, showing its role in zG function and linking its variants to primary aldosteronism and a new form of familial hypoaldosteronism.