Author

Loredana Le Pera

Institute of Molecular Biology and PathologyORCID 0000-0002-0076-9878Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alfredo PagliucaiD· 1 shared Angela Alessandra Alagia· 1 shared Annapaola FranchittoiD· 1 shared Assunta Maria CasaleiD· 1 shared Benedetta Perdichizzi· 1 shared Daniela Merlo· 1 shared Fabrizia NoroiD· 1 shared Flavia Di Feo· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Alfredo PagliucaORCID

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2 papers

Recent·Most cited

Subthreshold perturbation of DNA replication induces a secretory response and a bystander effect in naïve human fibroblasts

Benedetta Perdichizzi, Floriana Cappiello, Flavia Di Feo, Loredana Le Pera, Alfredo Pagliuca, Pasquale Valenzisi, Marco Rosina, Daniela Merlo, Annapaola Franchitto, Pietro Pichierri

The paper shows that low-dose DNA replication perturbation in fibroblasts triggers a secretory response and bystander effect without DNA damage.

bioRxiv · Aug 21, 2026 · PreprintCell Biology

Survival protection mechanisms and genetic variability induction after stress: two sides of the same Hsp70 coin

Ugo Cappucci, Fabrizia Noro, Assunta Maria Casale, Laura Fanti, Maria Francesca Berloco, Angela Alessandra Alagia, Luigi Grassi, Loredana Le Pera, Lucia Piacentini, Sergio Pimpinelli

This study shows that heat shock stress activates transposon expression by disrupting piRNA biogenesis through Hsp70's interaction with the Hsc70-Hsp90 complex in Drosophila.

bioRxiv · Sep 21, 2018 · PreprintGenetics