Katherine F. Vaeth

NET1 mRNA localization to the midbody is required for ARP2/3-dependent initiation of mitotic abscission

This study identifies NET1 mRNA localization to the midbody as essential for ARP2/3-dependent mitotic abscission by regulating protein expression and actin dynamics.

Rab40 GTPases regulate AMBRA1-mediated transcription and cell migration

This study identifies AMBRA1 as a binding partner of Rab40 GTPases, showing that Rab40/CRL5 ubiquitylates AMBRA1 to regulate gene transcription related to cell migration.

Ribosome Profiling Reveals Translational Reprogramming via mTOR Activation in Omacetaxine Resistant Multiple Myeloma

This study identifies translational reprogramming via mTOR activation as a mechanism of omacetaxine resistance in multiple myeloma and suggests combination therapy with mTOR inhibitors.

TDP-43 directly inhibits RNA accumulation in neurites through modulation of RNA stability

This study shows TDP-43 inhibits RNA accumulation in neurites by modulating RNA stability, with ALS mutations causing similar mislocalization.

The RNA binding protein HNRNPA2B1 regulates RNA abundance and motor protein activity in neurites

This study shows that HNRNPA2B1 prevents specific RNAs from localizing to neuronal projections, affecting motor protein transport and RNA stability.