Author

Patrícia Santos Barbosa

University of OxfordORCID 0000-0002-0138-3520Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Emilia K. TayloriD· 2 shared Georgia L. IsomiD· 2 shared Thomas Lanyon‐HoggiD· 2 shared Yiqiao WangiD· 2 shared Adam ThomasiD· 1 shared Elisabete C.C.M. MouraiD· 1 shared Frederik EiseleiD· 1 shared Hildur HreidarsdottiriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Emilia K. TaylorORCID

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Author profile →

2 papers

Recent·Most cited

Molecular Glue-like Degraders of TEM β-Lactamases by Periplasmic Protease DegP

Emilia K. Taylor, Patrícia Santos Barbosa, Tarini Kadambi, Frederik Eisele, Yiqiao Wang, Elisabete C.C.M. Moura, Timothy R. Walsh, Georgia L. Isom, Thomas Lanyon‐Hogg

This study develops molecular glue-like degraders that target TEM β-lactamases for degradation by DegP, showing improved synergy with piperacillin against resistant E. coli.

Angewandte Chemie · Oct 30, 2026Peer-reviewedMolecular Biology

Live-Cell Chemoproteomic Profiling Identifies the Uncharacterised Protein YbaA as a Direct Target of Ciprofloxacin in Escherichia coli

Tricia C.Y. Seow, Jacob D. Bradbury, Emilia K. Taylor, Ludwig G. Bauer, Madia Harvey, Hildur Hreidarsdottir, Soraya M. Saghbini, Yiqiao Wang, Adam Thomas, Patrícia Santos Barbosa, K. Huber, Georgia L. Isom, Thomas Lanyon‐Hogg

This study identifies YbaA as a new ciprofloxacin-binding protein in E. coli using AfBPP and validates its interaction through genetic and biophysical assays.

bioRxiv · Oct 16, 2025 · PreprintMicrobiology