Author

Zhixiao Su

Johns Hopkins UniversityORCID 0000-0002-0138-7433Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Organism:Drosophila· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Jeremiah Y. CoheniD· 3 shared Adam K. GlaseriD· 1 shared Alessio Paolo BuccinoiD· 1 shared Alex T. PietiD· 1 shared Anish Bhaswanth ChakkaiD· 1 shared Anna J. Chang· 1 shared Atlas JordaniD· 1 shared Audrey McCutcheoniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Jeremiah Y. CohenORCID

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4 papers

Recent·Most cited

Topographic structure and function of locus coeruleus norepinephrine neurons

Zhixiao Su, Polina Kosillo, Kanghoon Jung, Shuonan Chen, Mathew T. Summers, Alex T. Piet, Han Hou, Kenta M. Hagihara, Drew Friedmann, Olivia Ho-Shing, Matthew I. Becker, Thomas Chartrand, Peter Grotz, Ella Hilton-VanOsdall, Margaret Lee, , Jeremiah Y. Cohen

The paper identifies topographic organization in locus coeruleus norepinephrine neurons, linking their morphology, gene expression, and activity to specific brain regions and learning-related behaviors.

bioRxiv · Apr 10, 2026 · PreprintNeuroscience

Two types of locus coeruleus norepinephrine neurons drive reinforcement learning

Zhixiao Su, Jeremiah Y. Cohen

Mouse locus coeruleus norepinephrine neurons split into wide-spike and thin-spike subtypes that oppositely encode positive reward prediction errors and reward omission to drive reinforcement learning.

bioRxiv · Dec 8, 2022 · PreprintNeuroscience

Punishment history biases corticothalamic responses to motivationally-significant stimuli

Federica Lucantonio, Zhixiao Su, Anna J. Chang, Bilal A. Bari, Jeremiah Y. Cohen

The paper shows that punishment history affects corticothalamic responses to relevant stimuli, leading to biased behavior in mice.

bioRxiv · Apr 6, 2020 · PreprintNeuroscience

Drosophila Fezf coordinates laminar-specific connectivity through cell-intrinsic and cell-extrinsic mechanisms

Jing Peng, Ivan J. Santiago, Curie Ahn, Burak Gür, C. Kimberly Tsui, Zhixiao Su, Chundi Xu, Aziz Karakhanyan, Marion Silies, Matthew Y. Pecot

The paper shows that dFezf coordinates laminar-specific connectivity in Drosophila by both cell-intrinsic and cell-extrinsic mechanisms.

eLife · Mar 7, 2018Peer-reviewedNeuroscience