Mathew T. Summers

3D-MAESTRO automates processing of large-scale volumetric brain microscopy data, enabling scalable and reproducible analysis of mouse brain structures.

The paper uses single-cell projection mapping in mice and marmosets to show that thalamocortical projections are spatially segregated in marmosets but follow a conserved gradient in both species.

The paper identifies topographic organization in locus coeruleus norepinephrine neurons, linking their morphology, gene expression, and activity to specific brain regions and learning-related behaviors.

The paper introduces THALMANAC, a resource for analyzing single-cell transcriptomic data of the thalamus, revealing gene expression patterns that support and refine thalamic nucleus parcellation.

The paper shows that correlated variability in neural populations leads to highly suboptimal sensory coding according to novel null models.

The paper shows that distinct inhibitory pathways control motion velocity and directional tuning in retinal ganglion cells, revealing a velocity-invariant mechanism for directional selectivity.