Abigail M. Benvie

Suppressing PDGFRβ Signaling Enhances Myocyte Fusion to Promote Skeletal Muscle Regeneration

This study identifies PDGFRβ signaling as a regulator of myocyte fusion and muscle regeneration, showing that its suppression enhances muscle repair and myofiber size.

Reversing Pdgfrβ Signaling Restores Metabolically Active Beige Adipocytes by Alleviating ILC2 Suppression in Aged and Obese Mice

This study shows that reversing Pdgfrβ signaling in aged and obese mice restores beige adipocyte formation and improves metabolism by enhancing ILC2 activity.

Remodeling of gene regulatory networks underlying thermogenic stimuli-induced adipose beiging

This study identifies common and distinct chromatin accessibility changes in adipose tissue from mice exposed to cold or Adrb3 agonists, revealing unique functional consequences of these stimuli on lipid composition and thermogenesis.