Author

Lionel Blanc

Feinstein Institute for Medical ResearchORCID 0000-0002-0185-6260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

Julien PapoiniD· 2 shared Adrianna VlachosiD· 1 shared Ah Ram Kim· 1 shared Amy J. LambertiD· 1 shared Anne D. Koniski· 1 shared Anupama NarlaiD· 1 shared Babette GwynniD· 1 shared Bin ZhangiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

Julien PapoinORCID

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Author profile →

4 papers

Recent·Most cited

DDX41 dissolves G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death

Honghao Bi, Kehan Ren, Pan Wang, Ermin Li, Xu Han, Wen Wang, Jing Yang, Inci Aydemir, Kara Tao, Renee Ma, Lucy A. Godley, Yan Liu, Vipul Shukla, Elizabeth T. Bartom, Yuefeng Tang, , Peng Ji

Nature Communications · Aug 5, 2025Peer-reviewedCancer Biology

BMI1 regulates human erythroid self-renewal through both gene repression and gene activation

Kathleen E. McGrath, Jayme L. Olsen, Anne D. Koniski, Kristin E. Murphy, Michael Getman, Hyun Hyung An, Vincent P. Schulz, Ah Ram Kim, Bin Zhang, Taylor L. Carlson, Julien Papoin, Lionel Blanc, Paul D. Kingsley, Connie M. Westhoff, Patrick G. Gallagher, , James Palis

This study shows BMI1 promotes erythroid self-renewal through both gene repression and activation, offering a strategy to expand immature erythroid precursors for clinical use.

bioRxiv · Feb 2, 2024Cell Biology

Differential Effects of RASA3 Mutations on Hematopoiesis are Profoundly Influenced by Genetic Background and Molecular Variant

Raymond F. Robledo, Steven L. Ciciotte, Joel H. Graber, Yue Zhao, Amy J. Lambert, Babette Gwynn, Nathaniel J. Maki, Elena C. Brindley, Emily Hartman, Lionel Blanc, Luanne L. Peters

The paper investigates how RASA3 mutations affect hematopoiesis, showing that genetic background and molecular variant significantly influence disease outcomes in mouse models.

PLoS Genetics · Dec 28, 2020Peer-reviewedGenetics

Glucocorticoids Induce the Expansion of an Immature Human CFU-E Population

Ryan Ashley, Hongxia Yan, Nan Wang, John Hale, Brian M. Dulmovits, Julien Papoin, Meagan E. Olive, Namrata D. Udeshi, Steven A. Carr, Adrianna Vlachos, Jeffrey Michael M Lipton, Lydie M. Da Costa, Christopher D. Hillyer, Sandrina Kinet, Naomi N. Taylor, , Lionel Blanc

This study shows glucocorticoids expand immature CFU-E cells in peripheral blood but not cord blood, with p57Kip2 playing a key role in this effect.

bioRxiv · Aug 2, 2019 · PreprintDevelopmental Biology