Author

Hyun Hyung An

University of PennsylvaniaORCID 0000-0002-7070-8552Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alyssa Saito· 1 shared Ana Domingo-Meulas· 1 shared Andrew J. ModzelewskiiD· 1 shared Ariana D. CampbelliD· 1 shared Beril Tore· 1 shared Chantal K. Diallo· 1 shared Chia-Hui Chen· 1 shared David H. SongiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperDevelopmental Biology

Alyssa Saito

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3 papers

Recent·Most cited

An Intronic SINE at Pou5f1 Links Hormone Signaling to Blastocyst Hatching

Youjia Guo, Hyun Hyung An, Katelyn Toohill, Sneha Ramesh Mani, Ten D. Li, Chantal K. Diallo, Diego Antonio Jimenez, Alyssa Saito, Nicolae Adrian Leu, Beril Tore, Jamie Yoon Ha, Vamshidhar C. Nallamala, Sarah Stanger, Piotr Tetlak, Yanlin Hou, , Andrew J. Modzelewski

This study identifies an intronic SINE element that regulates Pou5f1/OCT4 repression in mouse trophectoderm, linking hormone signaling to blastocyst hatching and implantation.

bioRxiv · Aug 26, 2026 · PreprintDevelopmental Biology

Restraint of TGFβ family signaling by SMAD7 is necessary for hematopoietic stem cell maturation in the embryo.

Laura F. Bennett, Wenbao Yu, Chia-Hui Chen, Hyun Hyung An, Joanna M. Tober, Kai Tan, Nancy A. Speck

This study shows that SMAD7 restrains TGFβ and BMP signaling to enable pre-HSC maturation into HSCs during embryonic hematopoiesis.

bioRxiv · Aug 23, 2025 · PreprintDevelopmental Biology

Human erythroid progenitors express antigen presentation machinery

Rebecca L. Clements, Elizabeth A. Kennedy, David H. Song, Ariana D. Campbell, Hyun Hyung An, Kevin R. Amses, Taylor Miller-Ensminger, Mary M. Addison, Laurence Crane Eisenlohr, Stella T. Chou, Kellie Ann Jurado

The paper identifies human erythroid progenitors as immune mediators expressing MHC class II machinery and interacting with T cells in the fetal liver.

bioRxiv · Jun 27, 2024 · PreprintImmunology