Shai Carmi

The paper develops statistical tests to detect deviations from Hardy-Weinberg equilibrium on the X chromosome in sex-biased admixed populations, showing improved performance over existing methods.

FactorialHMM provides fast exact inference for factorial hidden Markov models, enabling efficient state sequence and likelihood computation with linearithmic time and space complexity.

The paper analyzes genetic and environmental factors in Israeli kibbutzim to identify cardiometabolic trait associations and population structure.

The paper measures DNA replication timing in mouse germline cells and shows it strongly correlates with mutation rates, recombination hotspots, and genomic features compared to somatic tissues.

This study investigates the ability to re-identify individuals through long-range familial searches in consumer genomics databases, finding that half of European-descent searches could yield close matches enabling re-identification.

The paper sequenced a population-specific reference panel at high depth to improve imputation accuracy and variant filtering in the Ashkenazi Jewish population.

This study shows environmental factors have a greater impact on human gut microbiota than host genetics, with microbiome data adding significant predictive value to phenotypes.

This paper investigates the timing and geographic origin of European admixture in Ashkenazi Jews using genetic methods and simulations, finding two admixture events: one Southern European pre-founder event and one Eastern European post-founder event.