LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes
Jin Li, Yamei Deng, Marie Gasser, Jie Zhu, Emily M. Walker, Vaibhav Sidarala, Emma C. Reck, Dre L. Hubers, Mabelle B. Pasmooij, Chun-Shik Shin, Khushdeep Bandesh, Eftyhmios Motakis, Siddhi Nargund, Romy Kursawe, Venkatesha Basrur, , Scott A. Soleimanpour
This study identifies LONP1's role in mitochondrial protein folding and shows its impact on beta cell survival and hyperglycemia in type 2 diabetes.
Nature Metabolism · Jul 21, 2025Peer-reviewedCell Biology