Author

Simon D. Bamforth

Newcastle UniversityORCID 0000-0002-5666-4485Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Helen M. PhillipsiD· 2 shared Timothy J. MohuniD· 2 shared Anastasia I. KousaiD· 1 shared Andrew D SharrocksiD· 1 shared Andrew D.H. Morgan· 1 shared Bjarke Krogstrup JenseniD· 1 shared Catherine A. Stothard· 1 shared Chloe O'Loughlin· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersGenetics

Helen M. PhillipsORCID

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Author profile →

4 papers

Recent·Most cited

A cell atlas of the developing human outflow tract of the heart and its adult aortic valve derivatives

Rotem Leshem, Syed Murtuza Baker, Joshua Mallen, Lu Wang, John Henry Dark, Andrew D Sharrocks, Karen Piper Hanley, Neil A. Hanley, Magnus Rattray, Simon D. Bamforth, Nicoletta Bobola

This study presents a transcriptomic atlas of the developing human outflow tract and its adult aortic valve derivatives, revealing persistent embryonic signatures and key regulatory factors in valve development.

eLife · Jun 25, 2026Peer-reviewedDevelopmental Biology

A Slc5a6 Deficient Mouse Model Reveals a Metabolically Driven Dilated Cardiomyopathy with Therapeutic Potential for Vitamin-Based Intervention

Millie Fullerton, Lauren C. Phillips, Rachael E. Redgrave, Luke Spray, Vincent Haufroid, George Merces, Scott T. Kerridge, Gavin D. Richardson, Nathalie Mercier, Dominique Roland, Rebecca Crossley, Andrew D.H. Morgan, Joseph P. Dewulf, John Burn, Simon D. Bamforth, Helen M. Phillips

This study shows that SLC5A6 deficiency causes dilated cardiomyopathy in mice, which can be prevented by vitamin supplementation, mirroring clinical outcomes in patients.

JCI Insight · Jun 2, 2026Peer-reviewedGenetics

The changing morphology of the ventricular walls of mouse and human with increasing gestation.

Bjarke Krogstrup Jensen, Yun Hee Chang, Simon D. Bamforth, Timothy J. Mohun, David Sedmera, Martin Bartoš, Robert Henry Anderson

The paper quantitatively and morphologically analyzes the development of ventricular walls in mouse and human hearts, finding that slow trabecular layer growth, not compaction, drives morphological changes.

Journal of Anatomy · Jan 29, 2024Peer-reviewedDevelopmental Biology

Pax9 is required for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to control 4th pharyngeal arch artery morphogenesis.

Helen M. Phillips, Catherine A. Stothard, Wasay Mohiuddin Shaikh Qureshi, Anastasia I. Kousa, J. Alberto Briones-Leon, Ramada R. Khasawneh, Chloe O'Loughlin, Rachel Sanders, Silvia Mazzotta, Rebecca Dodds, Kerstin Seidel, Timothy John Bates, Mitsushiro Nakatomi, Simon Cockell, Jürgen E. Schneider, , Simon D. Bamforth

The paper shows Pax9 is essential for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to regulate 4th pharyngeal arch artery formation.

Development · Jan 1, 2019Peer-reviewedDevelopmental Biology