Author
Victoria University of WellingtonORCID 0000-0002-0234-7206Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Jamie R. H. Taka, James Jung, Shuning Guo…·Ghader Bashiri
The paper uses time-resolved cryo-EM to show how acetyl-CoA binding induces conformational changes in ICL2, leading to asymmetric catalytic activity.
Evelyn Yu‐Wen Huang, Brooke X. C. Kwai, Wanting Jiao…·Ivanhoe K. H. Leung
This paper identifies how acetyl-CoA binding induces allostery in Mycobacterium tuberculosis ICL2, revealing a novel mechanism for enzyme activation and potential therapeutic targets.
Keely E.A. Oldham, Wanting Jiao, Erica J. Prentice, Joanna Hicks
The paper identifies a novel inhibitor of serine acetyltransferase from Neisseria gonorrhoeae with an IC50 of 13.9 μM through virtual screening.