Richard J. Price

Focused Ultrasound Blood-Tumor Barrier Opening Rapidly Augments Intratumor CD4 and CD8 T Cell Representation in a Genetically Engineered Mouse Model of Glioma

This study shows that focused ultrasound with microbubbles opens the blood-tumor barrier in a glioma model, increasing CD4 and CD8 T cell infiltration without altering the CD8/Treg ratio.

VEGFR2 blockade converts thermally ablative focused ultrasound into a potent driver of T cell-dependent anti-tumor immunity

This study combines thermally ablative focused ultrasound with VEGFR2 blockade to enhance T cell-dependent anti-tumor immunity and synergize with checkpoint inhibition.

Focused Ultrasound Crosslinkable Granular Hydrogels

This paper develops a FUS-responsive granular hydrogel system that stabilizes through crosslinking and porosity control, showing potential for minimally invasive tissue regeneration.

Focused Ultrasound Augments the Delivery and Penetration of Model Therapeutics into Cerebral Cavernous Malformations

This study evaluates how focused ultrasound enhances drug delivery into cerebral cavernous malformations using contrast agents in a mouse model.

Dynamics of Adult Axin2 Cell Lineage Integration in Granule Neurons of the Dentate Gyrus

The paper traces Axin2-positive cell lineage in adult hippocampal neurons, finding that Axin2 is expressed at multiple stages of differentiation and that integration of adult-born neurons can take longer than previously thought.

Understanding Lesion Progression in a Chronic Model of Cerebral Cavernous Malformations through Combined MRI and Histology

This study uses a chronic mouse model of CCM to analyze lesion progression with MRI and histology, revealing non-monotonous growth patterns and correlations between cell density and lesion stability.