Joan T. Richtsmeier

A dysmorphic mouse model reveals developmental interactions of chondrocranium and dermatocranium

This study uses 3D reconstructions of mouse chondrocranium and dermatocranium to show how a Fgfr2 variant affects their development and interaction.

The first transchromosomic rat model with human chromosome 21 shows robust Down syndrome features

The paper develops a transchromosomic rat model with human chromosome 21 that exhibits key Down syndrome features and provides a tool for DS research and drug development.

Quantification of gene expression patterns to reveal the origins of abnormal morphogenesis

This study develops a method to trace the origins of phenotypic abnormalities by quantifying 3D gene expression patterns in developing organs, revealing subtle gene expression differences in Apert syndrome models.