Author

Danny Orton

Pacific Northwest National LaboratoryORCID 0000-0002-0253-6859Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Alexey I. NesvizhskiiiD· 1 shared Andrey V. LiyuiD· 1 shared Benjamin M. Bumgarner· 1 shared Chia‐Feng TsaiiD· 1 shared Clive Henry WasserfalliD· 1 shared David ScholteniD· 1 shared Demirkan Besim Gursel· 1 shared Fengchao YuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Alexey I. NesvizhskiiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Single-Cell Proteomics of Human Peripheral Blood Mononuclear Cells Exceeding 600 Cells per Day

James M. Fulcher, Yumi Kwon, Pranav Dawar, Rashmi Kumar, Sarah M. Williams, Patricia J. Miller, Andrey V. Liyu, Liang Chen, Danny Orton, Heather M. Olson, Fengchao Yu, Alexey I. Nesvizhskii, Julie M. Fortier, Ravi Vij, Reyka G. Jayasinghe, , Ljiljana Pasa-Tolic

This paper develops a high-throughput single-cell proteomic method for PBMCs, achieving 660 cells per day with 750 protein identifications per cell and identifying low-frequency cell types.

bioRxiv · Feb 3, 2026 · PreprintImmunology

Robust collection and processing for label-free single voxel proteomics

Reta Birhanu Kitata, Marija Veličković, Zhangyang Xu, Rui Zhao, David Scholten, Rosalie Chu, Danny Orton, William Chrisler, Tong Zhang, Jeremy Abraham Mathews, Benjamin M. Bumgarner, Demirkan Besim Gursel, Ronald Jay Moore, Paul Piehowski, Tao Liu, , Tujin Shi

This paper introduces a method for label-free single voxel proteomics using wcSOP, enabling spatial resolution of protein expression in tissue samples.

Nature Communications · Jan 13, 2025Peer-reviewedMolecular Biology