Author

Zhangyang Xu

Pacific Northwest National LaboratoryORCID 0000-0002-0314-9244Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:protein folding & dynamics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Reta Birhanu KitataiD· 2 shared Rui ZhaoiD· 2 shared Tao LiuiD· 2 shared Tujin ShiiD· 2 shared Benjamin M. Bumgarner· 1 shared Carolina ReduzziiD· 1 shared Chia‐Feng TsaiiD· 1 shared Clive Henry WasserfalliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBiochemistry

Reta Birhanu KitataORCID

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2 papers

Recent·Most cited

Improved surfactant-assisted one-pot sample preparation for robust convenient single cell proteomics

Reta Birhanu Kitata, Zhangyang Xu, Nadia Bayou, Rui Zhao, William B. Chrisler, Matthew J. Gaffrey, Karl Weitz, Mara Serena Serafini, Elisabetta Molteni, Vladislav Petyuk, Massimo Cristofanilli, Tao Liu, Carolina Reduzzi, Tujin Shi

This paper introduces an improved single-cell proteomics method, iSOP-MS, which enhances robustness and convenience for quantitative analysis by using a low-volume 384-well plate and optimized enzyme mixtures.

Journal of Proteome Research · Jul 10, 2026Peer-reviewedBiochemistry

Robust collection and processing for label-free single voxel proteomics

Reta Birhanu Kitata, Marija Veličković, Zhangyang Xu, Rui Zhao, David Scholten, Rosalie Chu, Danny Orton, William Chrisler, Tong Zhang, Jeremy Abraham Mathews, Benjamin M. Bumgarner, Demirkan Besim Gursel, Ronald Jay Moore, Paul Piehowski, Tao Liu, , Tujin Shi

This paper introduces a method for label-free single voxel proteomics using wcSOP, enabling spatial resolution of protein expression in tissue samples.

Nature Communications · Jan 13, 2025Peer-reviewedMolecular Biology