Tong Zhang

This paper uses integrated PTM proteomics to show that Ref-1 inhibition rapidly remodels redox and mitochondrial signaling in pancreatic cancer cells.

ProteoMeter integrates multi-PTM and limited proteolysis data to map proteomic changes to residue level, demonstrating its use in analyzing HCoV-229E infection.

This paper identifies conserved transcriptional modules in Prochlorococcus MED4 using RNA-seq data and independent component analysis, revealing core regulatory programs that persist despite extreme genome reduction.

This study shows that activating AMPK alpha2 T172 in skeletal muscle improves exercise performance and energy transduction, and its disruption mimics type 2 diabetes features.

This paper introduces a method for label-free single voxel proteomics using wcSOP, enabling spatial resolution of protein expression in tissue samples.