Sarah M. Williams

Spatiotemporal Systems Biology Reveals Unique Cell-Type-Specific Carbon Metabolism Responses to Combined Abiotic Stresses in Poplar

This study identifies cell-type-specific carbon metabolism changes in poplar under combined abiotic stresses using multi-omics approaches.

The anaerobic fungus Caecomyces churrovis produces H2 via a non-bifurcating NADH-dependent enzyme complex

This paper identifies a non-bifurcating NADH-dependent enzyme complex in anaerobic fungi responsible for H2 production, distinct from ferredoxin-dependent pathways.

Single-cell nanodroplet processing proteomics pipeline for analysis of human-derived microglia

This paper introduces a single-cell proteomics pipeline for analyzing human microglia, identifying 1039 proteins per cell and revealing mitochondrial protein variation across subtypes.

Single-Cell Proteomics of Human Peripheral Blood Mononuclear Cells Exceeding 600 Cells per Day

This paper develops a high-throughput single-cell proteomic method for PBMCs, achieving 660 cells per day with 750 protein identifications per cell and identifying low-frequency cell types.

Single-cell proteomics of Arabidopsis leaf mesophyll identifies drought stress-related proteins

This study applies single-cell proteomics to Arabidopsis leaf mesophyll cells to identify drought stress-related proteins and changes in protein networks.

High-throughput Single-Cell Proteomics and Transcriptomics from the Same Cells with a Nanoliter-Scale Spin-Transfer Approach

The paper introduces nanoSPINS, a platform for high-throughput single-cell multiomics that integrates transcriptomic and proteomic profiling from the same cells, demonstrating improved throughput and statistical power.