Tanel Tenson

The paper uses single-cell analysis to show YbeX and YbeY have distinct roles in ribosome biogenesis in E. coli, with YbeX causing heterogeneous pre-rRNA processing and YbeY affecting 16S rRNA maturation.

The paper predicts structures for 27,000 viral proteins using AlphaFold2, revealing conserved folds across viruses infecting bacteria, archaea, and eukaryotes and identifying a new antiviral toxin-antitoxin system.

This study uses nanomotion technology to rapidly test Salmonella enterica's susceptibility to azithromycin, showing correlation with traditional susceptibility measures.

This study identifies 39 compounds active against non-growing uropathogenic E. coli and some against intracellular Shigella flexneri, with several showing selective activity against non-growing bacteria.

This study shows that repeated antibiotic use in humans leads to microbiota changes that impair intestinal mucus function in mice.

This study identifies and characterizes two Escherichia coli TAC systems that mediate antiphage defense by recognizing phage proteins and modifying mRNA to inhibit translation.

This study identifies YlmH as a novel RQC factor in B. subtilis, showing it can replace RqcP in polyalanine tail addition and is conserved in bacteria lacking RqcP.

This study evaluates differential expression analysis in HT-Seq by analyzing p-value distributions across datasets, finding widespread bias and inconsistent results.

The paper analyzes ABCF ATPases across 4505 genomes to uncover their diversity, subfamily relationships, and roles in antibiotic resistance and ribosome function.

PhenotypeSeeker predicts bacterial phenotypes from genomic sequences with high accuracy using k-mer-based models, achieving fast inference on assembled genomes.