Author

Paulo Amaral

University of CambridgeORCID 0000-0002-6696-5142Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:machine learning (classical)· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Glória Regina FrancoiD· 2 shared Helder Imoto NakayaiD· 2 shared Thomaz Lüscher DiasiD· 2 shared Tony KouzaridesiD· 2 shared Adrien LégeriD· 1 shared Ali M. Harandi· 1 shared Andre Goncalves· 1 shared Anton James EnrightiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersSystems Biology

Glória Regina FrancoORCID

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Author profile →

4 papers

Recent·Most cited

Long Non-Coding RNAs in Response to Ebola Virus Vaccine-Induced Immunity

Izabela Mamede, Thomaz Lüscher Dias, Isabelle Franco Moscardini, Patrícia Gonzalez‐Dias, Barbara Marinho, Fernando Marcon, Thiago Dominguez Crespo Hirata, M.J. Eichberg, Donata Medaglini, Ali M. Harandi, Claire‐Anne Siegrist, Tom H. M. Ottenhoff, Francesco Santoro, Marylyn M. Addo, Andre Goncalves, , Helder Imoto Nakaya

The paper identifies lncRNA expression signatures associated with Ebola vaccine-induced immunity using RNA-sequencing data from three human cohorts.

Frontiers in Immunology · Feb 10, 2026Peer-reviewedSystems Biology

The evolution of knowledge on genes associated with human diseases

Thomaz Lüscher Dias, Rodrigo Juliani Siqueira Dalmolin, Paulo Amaral, Tiago Lubiana Alves, Viviane Schuch, Glória Regina Franco, Helder Imoto Nakaya

This study tracks the evolution of gene-disease associations over 30 years using text-mining to reveal shared mechanisms and drug targets across diseases.

iScience · Dec 11, 2021Peer-reviewedGenetic & Genomic Medicine

RNA modifications detection by comparative Nanopore direct RNA sequencing

Adrien Léger, Paulo Amaral, Luca Pandolfini, Charlotte Capitanchik, Federica Capraro, Valentina Miano, Valentina Migliori, Patrick Toolan-Kerr, Theodora C. Sideri, Anton James Enright, Konstantinos Tzelepis, Folkert Jacobus van Werven, Nicholas M. Luscombe, Isaia Barbieri, Jernej Ule, , Tony Kouzarides

The paper introduces Nanocompore, a method to detect RNA modifications using Nanopore direct RNA sequencing, validated on human polyA+ RNAs and non-coding RNAs.

Nature Communications · Dec 10, 2021Peer-reviewedGenomics

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells

Samudyata Samudyata, Paulo Amaral, Pär G. Engström, Samuel C. Robson, Michael Lund Nielsen, Tony Kouzarides, Gonçalo Castelo‐Branco

The paper identifies RNA binding proteins and RNAs interacting with Sox2 in mouse embryonic stem cells, showing coexistence in a ribonucleoprotein complex without evidence of chromatin recruitment regulation.

Experimental Cell Research · May 9, 2019Peer-reviewedMolecular Biology