Author

Aleksa Milosavljevic

University of PennsylvaniaORCID 0000-0002-0282-034XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Andrew TsourkasiD· 1 shared Anit ShahiD· 1 shared Aparajeeta MajumderiD· 1 shared Breana ChanneriD· 1 shared Carolann L. EspyiD· 1 shared Christopher A. HunteriD· 1 shared Daniel W. ZuschlagiD· 1 shared Dennis E. DischeriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Andrew TsourkasORCID

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1 paper

Recent·Most cited

Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape without Side Effects

Serena Omo‐Lamai, Yufei Wang, Manthan N. Patel, Aleksa Milosavljevic, Daniel W. Zuschlag, Subhajit Poddar, Jichuan Wu, Liuqian Wang, Fengyi Dong, Carolann L. Espy, Aparajeeta Majumder, Eno‐Obong Essien, Mengwen Shen, Breana Channer, Tyler Ellis Papp, , Jacob Samuel Brenner

This paper identifies that lipid nanoparticle-induced inflammation arises from endosomal membrane damage and proposes strategies to mitigate it through galectin inhibition or ESCRT-recruiting lipids.

Nature Nanotechnology · Aug 11, 2025Peer-reviewedBioengineering