Author

Roy Matkovic

Centre National de la Recherche ScientifiqueORCID 0000-0002-0289-324XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Florence Margottin-GoguetiD· 2 shared Marina MoreliD· 2 shared Pauline LarrousiD· 2 shared Andrea CimarelliiD· 1 shared Benjamin MartiniD· 1 shared Cassandre GarnieriD· 1 shared Fabienne BejjaniiD· 1 shared Gaël CristofariiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Florence Margottin-GoguetORCID

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2 papers

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedApr 22, 2025

Deciphering lentiviral Vpr/Vpx determinants required for HUSH and SAMHD1 antagonism highlights the molecular plasticity of these evolutionary conflicts

Pauline Larrous, Cassandre Garnier, Marina Morel…·Florence Margottin-Goguet

This study identifies viral determinants in Vpr and Vpx proteins that enable antagonism of SAMHD1 and HUSH, revealing molecular plasticity in lentiviral adaptation to host restrictions.

3 citations

humanmouse

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Molecular BiologyNature CommunicationsPeer-reviewedJan 10, 2022

TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV

Roy Matkovic, Marina Morel, Sophie Lanciano…·Florence Margottin-Goguet

The paper shows TASOR interacts with CNOT1 and other RNA degradation factors to repress HIV expression by promoting RNA degradation and H3K9me3 deposition.

54 citationstop 4%

humanDNA methylation

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