Author

Kristian Helin

University of CopenhagenORCID 0000-0003-1975-6097Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Adam D. EwingiD· 1 shared Armando Reyes‐PalomaresiD· 1 shared Branavy Irayanar· 1 shared Christian ArnoldiD· 1 shared Darren TayloriD· 1 shared Dipta SenguptaiD· 1 shared Elias T. FrimaniD· 1 shared Francisco Jose Sanchez-LuqueiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperGenetics

Adam D. EwingORCID

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3 papers

Recent·Most cited

GenomicseLifePeer-reviewedFeb 17, 2026

Acetylation of H3K115 is detected associated with fragile nucleosomes at CpG island promoters and active regulatory sites

Yatendra Kumar, Dipta Sengupta, Elias T. Friman…·Wendy A. Bickmore

The paper identifies H3K115ac enrichment at fragile nucleosomes in promoters and enhancers, suggesting its role in nucleosome destabilization and regulatory element identification.

2 citations

mouseChIP-seq

𝕏 PostBluesky

GeneticsEpigenetics & ChromatinPeer-reviewedOct 16, 2023

Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation

Kevin C.L. Cheng, Jennifer M. Frost, Francisco Jose Sanchez-Luque…·Miguel Ramos Branco

This study shows that vitamin C increases young LINE-1 element expression in mouse ESCs through H3K9me3 demethylation by KDM4A/C, without increasing somatic insertion rates.

8 citations

mousehuman

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BioinformaticsCell ReportsPeer-reviewedDec 1, 2019

Quantification of differential transcription factor activity and multiomics-based classification into activators and repressors: diffTF

Ivan Berest, Christian Arnold, Armando Reyes‐Palomares…·Judith B. Zaugg

diffTF quantifies differential transcription factor activity and classifies TFs as activators or repressors using multi-omics data, identifying known and novel TFs in two case studies.

119 citationstop 3%

humanATAC-seq

𝕏 PostBluesky